The five-time world player of the year opened his account in the easiest possible fashion by tapping into an empty net from less than two metres in the 50th minute.
AC Milan have made a habit of muddling through under coach Massimiliano Allegri and they did it again on Wednesday by scraping into the Champions League knockout stage with a performance which left opponents Ajax Amsterdam fuming.
Juventus won a second consecutive double when substitute Alvaro Morata's extra-time goal secured a 1-0 Italian Cup final win over AC Milan who missed out on Europe for a third successive season on Saturday.
Pirlo started his first season in charge of a senior side looking to make it 10 successive Serie A titles for Juve, but the rookie coach struggled.
Bayern Munich were left to rue a number of missed chances in their Champions League last 16 first leg against Juventus on Tuesday after the Germans squandered a two-goal lead to draw 2-2 despite dominating for much of the game.
'There is a special bond in this team. There is something waiting to come out that is special. Hopefully that will come out next season'
Juventus defender Dani Alves produced an inspired display capped by a stunning volleyed goal in a 2-1 win over AS Monaco on Tuesday that took the Italians into their second Champions League final in three years.
Manchester City embark on a fifth Champions League campaign buoyant after a perfect start to their domestic season but still searching for the secret formula against Europe's top brass.
Juventus defeated second-placed Lazio 2-0 at home on Saturday to take another huge step towards their fourth straight Serie A title and boost their confidence for Wednesday's crunch Champions League clash in Monaco.
Cristiano Ronaldo and Lionel Messi will again be duelling for the title of world's best footballer after their names once again headed the shortlist on Thursday for The Best FIFA Men's Player.
Barcelona's hopes of staging another sensational Champions League comeback fell flat against a hardened Juventus side who held the Catalans to a 0-0 draw at the Nou Camp on Wednesday to reach the semi-finals 3-0 on aggregate.
Images from the Europa League semi-final first leg matches on Thursday.
A beautifully-worked Antonio Di Natale goal saw lowly Udinese beat AC Milan 1-0 in Serie A on Saturday to deal a huge blow to the visitors' prospects of European football next season.
Cristiano Ronaldo became the first player to score 400 goals in Europe's top five leagues as Juventus dropped points for the first time this season following a 1-1 Serie A draw with Genoa on Saturday. The Portuguese striker's fifth league goal for Juve carried him to the milestone, adding to his 84 strikes for Manchester United in the Premier League and 311 for Real Madrid in La Liga.
Juventus striker Carlos Tevez struck to give the Serie A champions a 1-0 win over AC Milan on Saturday, handing coach Massimiliano Allegri a winning return to San Siro where he was shown the door eight months ago.
The 19-year-old Mbappe followed up a domestic treble with Paris St Germain with a string of impressive performances in France's World Cup winning campaign.
Juventus striker Carlos Tevez scored a magnificent first-half goal, and later missed a penalty, as the runaway Serie A leaders won 1-0 at home to mid-table Genoa on Sunday.
Playmaker Kaka breathed new life into struggling AC Milan by scoring twice and 18-year-old Bryan Cristante claimed his first professional goal as they beat Atalanta 3-0 on Monday for only their fifth league win of the season.
Bayern Munich thrashed Bayer Leverkusen 5-1, while Barcelona came from behind to beat Valencia 3-1 in LaLiga at Camp Nou on Sunday.
Cristiano Ronaldo showed nerves of steel to score an injury-time penalty and send holders Real Madrid into the semi-finals of the Champions League in extraordinary circumstances as they lost 3-1 to Juventus on Wednesday but won a thrilling tie 4-3 on aggregate.
Cristiano Ronaldo scored with a bicycle kick which was outrageous even by his standards to lead Real Madrid to an emphatic 3-0 win away to Juventus in their Champions League quarter-final, first leg on Tuesday.
Real's Cristiano Ronaldo will be going in search of his third consecutive World Player of the Year award
Holders Chelsea made light of their off-pitch problems to reach the Champions League quarter-finals by beating Lille 2-1 away on Wednesday to complete a 4-1 aggregate victory.
Having battled to break down one of Europe's meanest defences in the quarter-finals, Real Madrid will have to do it all over again when they face Juventus in their Champions League semi-final.
News of all that's transpired on and off the football field
A round-up of Saturday's action in Serie A, La Liga and Bundesliga.
All the action that transpired on and off the football field
Cristiano Ronaldo was involved in all three of his team's goals as Juventus came from behind to beat Napoli 3-1 in a Serie A top-of-the-table clash on Saturday to maintain their perfect start to the season.
Last season's runners-up Liverpool, big-spending French league champions Paris St Germain and Carlo Ancelotti's Napoli were thrown together in the pick of the groups while holders Real Madrid must face last season's semi-finalists AS Roma.
A spectacular piledriver from Juan Cuadrado gave Serie A leaders Juventus a 1-0 win over Inter Milan, ending a run of seven successive Serie A wins for their opponents in a pulsating end-to-end match on Sunday.
Images from the UEFA Champions League matches played on Wednesday.
Images from the matches played across football leagues in Europe on Sunday.
Europa League kings Sevilla breezed past Manchester United into the semi-finals of their favourite competition as Youssef En Nesyri scored twice
AC Milan chief executive Adriano Galliani is to quit after 27 years at the Serie A club, he told the ANSA news agency on Friday.
AS Roma moved clear at the top of Serie A after beating Sampdoria 2-0 on Wednesday as struggling AC Milan came back from 3-1 down to draw 3-3 in stoppage time at Bologna.
Inter Milan got a crucial 1-0 win at Juventus on Sunday
A round-up of Wednesday's action in the UEFA Champions League.
Among other transfer news globally, defender Rahul Bheke joins Mumbai City FC while Locatelli completes Juventus move.
Juventus rehire Allegri.
Juventus did the bare minimum as they scraped into the Champions League knockout stage on Tuesday with a 0-0 draw at home to Atletico Madrid, a result which also suited the Spaniards who topped the group.